IGF-1LR3 10IU ALLEY insulin-like growth factor-I (IGF-1 Long R3) is a simple, non-glycosylated human recombinant, a 83-amino acid polypeptide chain. It is a human IGF-1 analog comprising IGF-1 human sequence complete with the substitution of arginine (Arg or R) for glutamic acid (Glu or E) at position 3 (where R 3) and An amino acid the peptide extension at the N-terminus.
Molecular weight: 9111.6 daltons – confirmed by mass spectrometry It is produced in E. coli using a patented expression system long IGF-I [R3] is properly folded and purified by several chromatography steps to give receptors of Quality of long IGF-I [R3].
IGF-1LR3 10IU ALLEY is apyrogenic sterile lyophilized white powder for subcutaneous or intramuscular injection, after reconstitution with sterile water for injection (0.3% m-cresol).
IGF-1LR3 10IU ALLEY mechanism of action
This analogue has been designed for the express purpose of increasing biological activity. IGF-1 Long R3 is significantly more potent than IGF1 in vitro and in vivo. The increased potency is due to the marked decrease in binding of the IGF-1 LongR3 all the IGF binding proteins. These binding proteins normally inhibit the biological actions of FGI.
IGF 1 is the insulin-like growth factor. It is a natural substance that is produced in the human body and is at its highest natural levels during puberty. During puberty IGF-1 is the most responsible for natural muscle growth that occurs during these few years. There are many different things that IGF1 does in the human body. Among the most positive effects are:
Increased transport of amino acids to cebuy
The increase in glucose transport
Increased protein synthesis
Decrease in protein degradation
Increase in RNA synthesis.
When IGF-1LR3 10IU ALLEY is active, it behaves differently in different types of tissue. In the muscle cells proteins and associated cellular components are stimulated. The synthesis of proteins is increased at the same time as the absorption of amino acids. As an energy source, IGF-1 mobilizes fat to be used as energy in adipose tissue. In lean tissue, IGF1 prevents insulin from transporting glucose through cell membranes. As a result, cells must switch to burning fat as a source of energy.
IGF-1LR3 10IU ALLEY also has mimetic insulin in the human body. It makes the muscles more sensitive to the effects of insulin, so if you are a person who currently uses insulin, you can reduce your dose by a decent margin to achieve the same effects, and as mentioned IGF 1 will keep insulin To make grow.
The most interesting and potent effect IGF1 on the human body is its ability to cause hyperplasia, which is an effective separation of cells. Hyperplasia is significantly different from hypertrophy. Hypertrophy is simply an increase in the size of muscle cells. After puberty, the human body has a determined number of muscle cells and hypertrophy is to increase the size of these muscle cells.
But IGF-1LR3 10IU ALLEY is capable of causing hyperplasia which increases the number of muscle cells present in the tissue. So, in a way IGF1 can actually change your genetic ability in terms of muscle tissue and the number of cells. Proliferates IGF-1 and differentiates the number of cell types present. At the genetic level, it has the potential to alter a person’s ability to build upper muscle density and size. Regular IGF-1 only has a half-life of about 10 to 20 minutes in the human body and is rapidly destroyed. The most effective analog IGF form of all is IGF-1 LR3. Because of its chemical modification and amino acid changes, IGF1 Long R3 can avoid binding to proteins in the human body, and therefore have a much longer half-life, about 20-30 hours.
IGF-1LR3 10IU ALLEY Side Effects
This list shows the most serious and / or most frequently harmful reactions observed using IGF-1 or its analogs:
Users may feel emptied and tired throughout the day. This seems to be one of the negative side effects to IGF-1LR3 10IU ALLEY, it will make you sleep longer and you will need more sleep at night to feel rested in the morning. This is also common with high doses of HGH